LGR5 Human Gene Knockout Kit (CRISPR)

CAT#: KN212825RB

LGR5 - human gene knockout kit via CRISPR, HDR mediated

SDS

HDR-mediated knockout kit validation

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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA RFP-BSD
Symbol LGR5
Locus ID 8549
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001277226, NM_001277227, NM_003667, NR_110596
Synonyms FEX; GPR49; GPR67; GRP49; HG38
Summary The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

Other Versions

SKU Description Size Price
KN212825 LGR5 - human gene knockout kit via CRISPR, HDR mediated
    • 1 kit

USD 1,290.00

KN212825BN LGR5 - human gene knockout kit via CRISPR, HDR mediated
    • 1 kit

USD 1,290.00

KN212825LP LGR5 - human gene knockout kit via CRISPR, HDR mediated
    • 1 kit

USD 1,290.00

KN412825 LGR5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

GA105663 LGR5 CRISPRa kit - CRISPR gene activation of human leucine rich repeat containing G protein-coupled receptor 5
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.