IL28 Receptor alpha (IFNLR1) Human Gene Knockout Kit (CRISPR)
CAT#: KN221789
IFNLR1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | IFNLR1 |
Locus ID | 163702 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_170743, NM_173064, NM_173065 |
Synonyms | CRF2/12; IFNLR; IL-28R1; IL28RA; LICR2 |
Summary | The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN221789BN | IFNLR1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN221789LP | IFNLR1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN221789RB | IFNLR1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN421789 | IFNLR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA116094 | IFNLR1 CRISPRa kit - CRISPR gene activation of human interferon lambda receptor 1 |
USD 1,290.00 |
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