Cgas Mouse Gene Knockout Kit (CRISPR)
CAT#: KN309828LP
Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | Cgas |
Locus ID | 214763 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_173386, NR_125721 |
Synonyms | cGAS; E330016A19Rik |
Summary | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN309828 | Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN309828BN | Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN309828RB | Mb21d1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN509828 | Mb21d1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA213232 | Cgas CRISPRa kit - CRISPR gene activation of mouse cyclic GMP-AMP synthase |
USD 1,290.00 |
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