PEA15 Human Gene Knockout Kit (CRISPR)

CAT#: KN405507

PEA15 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN405507 is the updated version of KN205507.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol PEA15
Locus ID 8682
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001297576, NM_001297577, NM_001297578, NM_003768, NM_013287, NR_123724
Synonyms HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PED
Summary This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Other Versions

SKU Description Size Price
GA105759 PEA15 CRISPRa kit - CRISPR gene activation of human proliferation and apoptosis adaptor protein 15
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.