SLC26A5 Human Gene Knockout Kit (CRISPR)
CAT#: KN412970
SLC26A5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN412970 is the updated version of KN212970.
USD 1,290.00
2 Weeks*
Size
Other products for "SLC26A5"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | SLC26A5 |
Locus ID | 375611 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001167962, NM_001321787, NM_198999, NM_206883, NM_206884, NM_206885, NR_120441, NR_120442, NR_120443, NR_135801, NR_135802 |
Synonyms | DFNB61; PRES |
Summary | This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA117826 | SLC26A5 CRISPRa kit - CRISPR gene activation of human solute carrier family 26 member 5 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.