Gnrh1 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN507104
Gnrh1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Gnrh1 |
Locus ID | 14714 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_008145, NR_133010 |
Synonyms | Gnrh; Gnrh2; hpg; LHRH; Lhrh1; Lnrh |
Summary | This gene encodes hypophysiotropic peptides belonging to the family of gonadotropin-releasing hormones that stimulate the release of gonadotropins and suppress secretion of prolactin from the pituitary gland. The encoded protein is proteolytically processed to generate two biologically active mature peptides. A deletional mutation encompassing the distal half of this gene in mice resulting in the loss of the encoded protein leads to hypogonadism and infertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
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KN307104 | Gnrh1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN307104BN | Gnrh1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN307104LP | Gnrh1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN307104RB | Gnrh1 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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GA201677 | Gnrh1 CRISPRa kit - CRISPR gene activation of mouse gonadotropin releasing hormone 1 |
USD 1,290.00 |
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