Plunc (BPIFA1) (NM_016583) Human Mass Spec Standard

CAT#: PH313322

PLUNC MS Standard C13 and N15-labeled recombinant protein (NP_057667)

Product Images

Coomassie blue staining of purified BPIFA1 protein (Cat# TP313322). The protein was produced from HEK293T cells transfected with BPIFA1 cDNA clone (Cat# RC213322) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC213322
• Predicted MW: 26.71 kDa
• Protein Sequence:
  Sequence Link

  >RC213322 representing NM_016583
  Red=Cloning site Green=Tags(s)
  
  MFQTGGLIVFYGLLAQTMAQFGGLPVPLDQTLPLNVNPALPLSPTGLAGSLTNALSNGLLSGGLLGILEN
  LPLLDILKPGGGTSGGLLGGLLGKVTSVIPGLNNIIDIKVTDPQLLELGLVQSPDGHRLYVTIPLGIKLQ
  VNTPLVGASLLRLAVKLDITAEILAVRDKQERIHLVLGDCTHSPGSLQISLLDGLGPLPIQGLLDSLTGI
  LNKVLPELVQGNVCPLVNEVLRGLDITLVHDIVNMLIHGLQFVIKV
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_057667
• RefSeq Size: 1049
• RefSeq ORF: 768
• Synonyms: bA49G10.5; LUNX; NASG; PLUNC; SPLUNC1; SPURT
• Locus ID: 51297
• UniProt ID: Q9NP55
• Cytogenetics: 20q11.21
• Summary: This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014]
• Protein Families: Secreted Protein