XTP3TPA (DCTPP1) (NM_024096) Human Recombinant Protein

CAT#: TP301727

Recombinant protein of human dCTP pyrophosphatase 1 (DCTPP1)

Product Images

Coomassie blue staining of purified DCTPP1 protein (Cat# TP301727). The protein was produced from HEK293T cells transfected with DCTPP1 cDNA clone (Cat# RC201727) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  >RC201727 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLALVGEVGELAEL
  FQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLSKMDINRRRYPAHLARSSSRK
  YTELPHGAISEDQAVGPADIPCDSTGQTST
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Tag: C-Myc/DDK
• Predicted MW: 18.5 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Note: For culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_077001
• Locus ID: 79077
• UniProt ID: Q9H773
• Cytogenetics: 16p11.2
• Refseq Size: 1143
• Refseq ORF: 510
• Synonyms: CDA03; RS21C6; XTP3TPA
• Summary: The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]
• Protein Families: Stem cell - Pluripotency