Zyxin (ZYX) (NM_003461) Human Recombinant Protein
CAT#: TP314079
Recombinant protein of human zyxin (ZYX), transcript variant 1
Special Offer: Get a 20% discount on this product. Use code: "MVPro20".
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
Recombinant protein was produced with TrueORF clone, RC214079. Click on the TrueORF clone link to view cDNA and protein sequences.
|
Tag | C-Myc/DDK |
Predicted MW | 61.1 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_003452 |
Locus ID | 7791 |
UniProt ID | Q15942, Q96AF9 |
Cytogenetics | 7q34 |
Refseq Size | 2325 |
Refseq ORF | 1716 |
Synonyms | ESP-2; HED-2 |
Summary | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008] |
Protein Pathways | Focal adhesion |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418663 | ZYX HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LY418663 | Transient overexpression lysate of zyxin (ZYX), transcript variant 1 |
USD 605.00 |
|
PH300960 | ZYX MS Standard C13 and N15-labeled recombinant protein (NP_001010972) |
USD 2,055.00 |
|
PH314079 | ZYX MS Standard C13 and N15-labeled recombinant protein (NP_003452) |
USD 2,055.00 |
|
TP300960 | Recombinant protein of human zyxin (ZYX), transcript variant 2 |
USD 867.00 |
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