G0 Protein alpha (GNAO1) (NM_020988) Human Recombinant Protein

CAT#: TP317958

Recombinant protein of human guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1), transcript variant 1

Product Images

Coomassie blue staining of purified GNAO1 protein (Cat# TP317958). The protein was produced from HEK293T cells transfected with GNAO1 cDNA clone (Cat# RC217958) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC217958. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 39.9 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_066268
• Locus ID: 2775
• UniProt ID: P09471, B3KP89, Q8N6I9
• Cytogenetics: 16q13
• Refseq Size: 3332
• Refseq ORF: 1062
• Synonyms: EIEE17; G-ALPHA-o; GNAO; HLA-DQB1; NEDIM
• Summary: 'The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]'
• Protein Families: Druggable Genome
• Protein Pathways: Long-term depression, Melanogenesis