Glutaredoxin 1 (GLRX) (NM_002064) Human Recombinant Protein

CAT#: TP319385

Recombinant protein of human glutaredoxin (thioltransferase) (GLRX), transcript variant 1

Product Images

Coomassie blue staining of purified GLRX protein (Cat# TP319385). The protein was produced from HEK293T cells transfected with GLRX cDNA clone (Cat# RC219385) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Recombinant protein was produced with TrueORF clone, RC219385. Click on the TrueORF clone link to view cDNA and protein sequences.
• Tag: C-Myc/DDK
• Predicted MW: 11.6 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_002055
• Locus ID: 2745
• UniProt ID: P35754, A0A024RAM2
• Cytogenetics: 5q15
• Refseq Size: 1328
• Refseq ORF: 318
• Synonyms: GRX; GRX1
• Summary: 'This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]'
• Protein Families: Druggable Genome