beta 2 Microglobulin (B2M) (NM_004048) Human Recombinant Protein

CAT#: TP710178

Recombinant protein of human beta-2-microglobulin (B2M), residues 21-119aa, secretory expressed with GP67 signal peptide, with C-terminal DDK tag, expressed in sf9, 20ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: Sf9
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, RC207587, encoding the region(Met-Ile21-Met119) of Homo sapiens B2M
• Tag: C-DDK
• Predicted MW: 12 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_004039
• Locus ID: 567
• UniProt ID: P61769
• Cytogenetics: 15q21.1
• Refseq Size: 987
• Refseq ORF: 357
• Synonyms: IMD43
• Summary: 'This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]'
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Antigen processing and presentation