Interferon gamma (IFNG) (NM_000619) Human Recombinant Protein
CAT#: TP720013
Recombinant protein of human interferon, gamma (IFNG)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Gln24-Gln166
|
Tag | tag free |
Predicted MW | 16.9 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mMTris-HCl,250mMNaCl,pH8.5. |
Bioactivity | Specific Activity is greater than 1.5 x 107 IU/mg as determined in a viral resistance assay using VSV-WISH cells. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_000610 |
Locus ID | 3458 |
UniProt ID | P01579 |
Cytogenetics | 12q15 |
Synonyms | IFG; IFI; IMD69 |
Summary | This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Allograft rejection, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Proteasome, Regulation of autophagy, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, Type I diabetes mellitus |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400207 | IFNG HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY400207 | Transient overexpression lysate of interferon, gamma (IFNG) |
USD 396.00 |
|
PH309993 | IFNG MS Standard C13 and N15-labeled recombinant protein (NP_000610) |
USD 2,055.00 |
|
TP309993 | Purified recombinant protein of Homo sapiens interferon, gamma (IFNG) |
USD 823.00 |
|
TP721239 | Purified recombinant protein of Human interferon, gamma (IFNG) |
USD 330.00 |
|
TP723162 | Purified recombinant protein of Human interferon, gamma (IFNG). |
USD 140.00 |
|
TP723709 | Purified recombinant protein of Human interferon, gamma (IFNG) |
USD 145.00 |
|
TP760490 | Purified recombinant protein of Human interferon, gamma (IFNG), with N-terminal HIS tag, expressed in E.Coli, 50ug |
USD 215.00 |
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