IL1RA (IL1RN) (NM_000577) Human Recombinant Protein
CAT#: TP720025
Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Arg26-Glu177
|
Tag | tag free |
Predicted MW | 17.3 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS,PH7.4. |
Bioactivity | ED50 is 0.5 ng/ml as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells. Specific Activity of 2.0 x 106 IU/mg. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_000568 |
Locus ID | 3557 |
UniProt ID | P18510 |
Cytogenetics | 2q14.1 |
Synonyms | DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4 |
Summary | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020] |
Protein Families | Druggable Genome, Secreted Protein |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403570 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC403571 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC406440 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC424628 | IL1RN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY403570 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 1 |
USD 396.00 |
|
LY403571 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 4 |
USD 396.00 |
|
LY406440 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 2 |
USD 396.00 |
|
LY424628 | Transient overexpression lysate of interleukin 1 receptor antagonist (IL1RN), transcript variant 3 |
USD 396.00 |
|
PH302447 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776215) |
USD 2,055.00 |
|
PH312460 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_000568) |
USD 2,055.00 |
|
PH318518 | IL1RN MS Standard C13 and N15-labeled recombinant protein (NP_776214) |
USD 2,055.00 |
|
TP302447 | Purified recombinant protein of Homo sapiens interleukin 1 receptor antagonist (IL1RN), transcript variant 4 |
USD 439.00 |
|
TP312460 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 3 |
USD 748.00 |
|
TP318518 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 1 |
USD 748.00 |
|
TP723209 | Purified recombinant protein of Human interleukin 1 receptor antagonist (IL1RN), transcript variant 3. |
USD 140.00 |
|
TP760033 | Recombinant protein of human interleukin 1 receptor antagonist (IL1RN), transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
USD 215.00 |
{0} Product Review(s)
Be the first one to submit a review