Myelin oligodendrocyte glycoprotein (MOG) (NM_001008228) Human Recombinant Protein

CAT#: TP720042

Recombinant protein of human myelin oligodendrocyte glycoprotein (MOG), transcript variant alpha3

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Gly30-Gly154
• Tag: C-His
• Predicted MW: 15.2 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Lyophilized from a 0.2 um filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5.
• Bioactivity: Tested for capability to induce EAE in rodents and monkeys
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001008229
• Locus ID: 4340
• UniProt ID: Q16653, Q16653-3
• Cytogenetics: 6p22.1
• Synonyms: BTN6; BTNL11; MOGIG2; NRCLP7
• Summary: The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
• Protein Families: Transmembrane