HMG1 (HMGB1) (NM_002128) Human Recombinant Protein
CAT#: TP720309
Recombinant protein of human high-mobility group box 1 (HMGB1)
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Gly2-Glu215
|
Tag | C-His |
Predicted MW | 25.9 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 20mM Phosphate buffer, 150mM NaCl, 1mM EDTA, 1mM DTT, 10% Glycerol, pH 7.4. |
Bioactivity | ELISA capture for autoantibodies (PMID: 28862243) |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Store at -80°C. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002119 |
Locus ID | 3146 |
UniProt ID | P09429, A0A024RDR0 |
Cytogenetics | 13q12.3 |
Synonyms | HMG-1; HMG1; HMG3; SBP-1 |
Summary | 'This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]' |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Base excision repair |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400775 | HMGB1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 99.00 |
|
LY400775 | Transient overexpression lysate of high-mobility group box 1 (HMGB1) |
USD 325.00 |
|
PH305918 | HMGB1 MS Standard C13 and N15-labeled recombinant protein (NP_002119) |
USD 2,055.00 |
|
TP305918 | Recombinant protein of human high-mobility group box 1 (HMGB1) |
USD 823.00 |
|
TP721133 | Purified recombinant protein of Human high mobility group box 1 (HMGB1) |
USD 300.00 |
|
TP721198 | Purified recombinant protein of Human high mobility group box 1 (HMGB1) |
USD 300.00 |
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