G CSF (CSF3) (NM_172220) Human Recombinant Protein

CAT#: TP723770

Purified recombinant protein of Human colony stimulating factor 3 (granulocyte) (CSF3), transcript variant 3


  View other "CSF3" proteins (13)

USD 265.00

5 Days*

Size
    • 10 ug

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Human G-CSF, the region of Thr27-Pro200 from gene Accession# BC033245.1
Tag Tag Free
Predicted MW 18.6 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity >95%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS
Bioactivity The ED50 is 0.02 - 0.08 ng/ml, corresponding to a specific activity of 1.25 - 5.0 x 10^7 units/mg, determined by M-NFS60 cell proliferation induced by human G-CSF in a dose dependent manner.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_757374
Locus ID 1440
UniProt ID P09919, Q8N4W3
Cytogenetics 17q21.1
Refseq Size 1494
Refseq ORF 600
Synonyms C17orf33; CSF3OS; GCSF
Summary 'This gene encodes a member of the IL-6 superfamily of cytokines. The encoded cytokine controls the production, differentiation, and function of granulocytes. Granulocytes are a type of white blood cell that are part of the innate immune response. A modified form of this protein is commonly administered to manage chemotherapy-induced neutropenia. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2020]'
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.