Creatine kinase M type (CKM) (NM_001824) Human Recombinant Protein

CAT#: TP750145

Purified recombinant heterodimer protein of Human CKMB(full length creatine kinase, muscle (CKM) with N-terminal GST tag, and full length creatine kinase, brain (CKB), with N-terminal His(CKB) tag), expressed in E.coli, 100ug

Product Images

Purified recombinant protein CKM/CKB was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the full length of CKM/CKB
• Tag: N-GST(CKM) and N-His(CKB)
• Predicted MW: 69.1 kDa/42.6 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 90% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 10 mM Tris, pH 7.2, 5 mM mercaptoethanol, 50% glycerol.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• Locus ID: 1158
• UniProt ID: P06732, B2R892
• Cytogenetics: 19q13.32
• Refseq Size: 1666
• Refseq ORF: 1143
• Synonyms: CKMM; CPK-M; M-CK
• Summary: 'The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways