Creatine kinase M type (CKM) (NM_001824) Human Recombinant Protein

CAT#: TP750145

Purified recombinant heterodimer protein of Human CKMB(full length creatine kinase, muscle (CKM) with N-terminal GST tag, and full length creatine kinase, brain (CKB), with N-terminal His(CKB) tag), expressed in E.coli, 100ug


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USD 299.00

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Size
    • 100 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the full length of CKM/CKB
Tag N-GST(CKM) and N-His(CKB)
Predicted MW 69.1 kDa/42.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 90% as determined by SDS-PAGE and Coomassie blue staining
Buffer 10 mM Tris, pH 7.2, 5 mM mercaptoethanol, 50% glycerol.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
Locus ID 1158
UniProt ID P06732, B2R892
Cytogenetics 19q13.32
Refseq Size 1666
Refseq ORF 1143
Synonyms CKMM; CPK-M; M-CK
Summary 'The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]'
Protein Families Druggable Genome
Protein Pathways Arginine and proline metabolism, Metabolic pathways

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