ARF6 Rabbit Polyclonal Antibody

CAT#: TA349245

Rabbit Polyclonal Anti-ARF6 Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-4: A431 cells human liver cancer tissue 231 cells human fetal liver tissue Primary antibody: TA349245 (ARF6 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA349245 (ARF6 Antibody) at dilution 1/20. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349245 (ARF6 Antibody) at dilution 1/20. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: A431 cells and human liver cancer tissue, 231 cells and human fetal liver tissue
  IHC: 25-100
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ARF6
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20 kDa
• Gene Name: ADP ribosylation factor 6
• Database Link:
  NP_001654
  Entrez Gene 11845 MouseEntrez Gene 79121 RatEntrez Gene 382 Human
  UniProt ID P62330
• Background: This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
• Synonyms: DKFZp564M0264

Reference Data

• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis