14-3-3 beta (YWHAB) Rabbit Polyclonal Antibody

CAT#: TA355455

YWHAB Antibody - middle region

Product Images

WB Suggested Anti-YWHAB Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human YWHAB
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
  Homology: Cow: 87%; Dog: 87%; Guinea Pig: 87%; Horse: 80%; Human: 87%; Mouse: 87%; Rabbit: 87%; Rat: 87%; Sheep: 87%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 28kDa
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
• Database Link:
  NP_003395
  Entrez Gene 7529 Human
  UniProt ID P31946
• Background: YWHAB belongs to the 14-3-3 family, members of which mediate signal transduction by binding to phosphoserine-containing proteins. YWHAB has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.
• Synonyms: GW128; HS1; KCIP-1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis