RGS20 Rabbit Polyclonal Antibody

CAT#: TA355649

RGS20 Antibody - N-terminal region

Product Images

WB Suggested Anti-RGS20 Antibody Titration: 1.0 ug/ml Positive Control: COLO205 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: 100% homologous to isoforms 1, 2, 4-6.
  
  Expected reactivity: Guinea Pig, Horse, Human, Mouse, Rat
  Homology: Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 85%; Rat: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 27kDa
• Gene Name: regulator of G-protein signaling 20
• Database Link:
  NP_003693
  Entrez Gene 8601 Human
  UniProt ID O76081
• Background: The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: G(z)GAP; Gz-GAP; RGSZ1; ZGAP1

Reference Data

• Protein Families: Druggable Genome