Ku70 (XRCC6) Rabbit Polyclonal Antibody
Other products for "XRCC6"
Specifications
Product Data | |
Applications | IHC, WB |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human G22P1 |
Specificity | Expected reactivity: Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat Homology: Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93% |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration | lot specific |
Purification | Protein A purified |
Conjugation | Unconjugated |
Storage | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Predicted Protein Size | 70kDa |
Gene Name | X-ray repair complementing defective repair in Chinese hamster cells 6 |
Database Link | |
Background | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. |
Synonyms | CTC75; CTCBF; D22S671; D22S731; G22P1; KU70; ML8; OTTHUMP00000199333; OTTHUMP00000199349; TLAA |
Reference Data | |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Non-homologous end-joining |
Documents
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.