PARK7 Rabbit Polyclonal Antibody

CAT#: TA356956

PARK7 Antibody - C-terminal region

Product Images

WB Suggested Anti-PARK7 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate

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  PARK7 antibody - C-terminal region (TA356956) validated by WB using SH-SY5Y cell line at 1: 500.PARK7 is supported by BioGPS gene expression data to be expressed in SHSY5Y

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  Sample Type: Mouse Brain Slices Red: primary Blue: DAPI Primary Dilution: 1:400 Secondary Antibody: Anti-Rabbit IgG Alexa 594 Secondary Dilution: 1:400 Image Submitted By: Adahir Labrador-Garrido and Cintia Roodveldt University of Seville

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PARK7
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 20kDa
• Gene Name: Parkinsonism associated deglycase
• Database Link:
  NP_009193
  Entrez Gene 57320 MouseEntrez Gene 11315 Human
  UniProt ID Q99497
• Background: PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7.The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
• Synonyms: DJ-1; DJ1; FLJ27376; FLJ34360; FLJ92274; OTTHUMP00000001350; OTTHUMP00000001351

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Parkinson's disease