Melatonin Receptor 1A (MTNR1A) Rabbit Polyclonal Antibody

CAT#: TA357890

MTNR1A Antibody - C-terminal region

Product Images

WB Suggested Anti-MTNR1A Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell

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  Host: Rabbit Target Name: HIRIP3 Sample Type: 293T Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Goat, Guinea Pig, Horse, Human, Rabbit, Sheep
  Homology: Cow: 79%; Dog: 91%; Goat: 79%; Guinea Pig: 82%; Horse: 83%; Human: 100%; Rabbit: 83%; Sheep: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 39kDa
• Gene Name: melatonin receptor 1A
• Database Link:
  NP_005949
  Entrez Gene 4543 Human
  UniProt ID P48039
• Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
• Synonyms: MEL-1A-R; MT1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction