FKBP12 (FKBP1A) Rabbit Polyclonal Antibody

CAT#: TA358866

FKBP1A Antibody - N-terminal region

Product Images

WB Suggested Anti-FKBP1A Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole CellFKBP1A is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells

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  Host: Mouse Target Name: FKBP1A Sample Tissue: Mouse Brain Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 93%; Zebrafish: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 12kDa
• Gene Name: FK506 binding protein 1A
• Database Link:
  NP_000792
  Entrez Gene 14225 MouseEntrez Gene 2280 Human
  UniProt ID P62942
• Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
• Synonyms: FKBP-1A; FKBP-12; FKBP1; FKBP12; FKBP12-Exip3; FKBP12C; PKC12; PKCI2; PPIASE; rotamase

Reference Data

• Protein Families: Druggable Genome