PMS2 Mouse Monoclonal Antibody [Clone ID: OTI2G5]

CAT#: TA506658S

PMS2 mouse monoclonal antibody, clone OTI2G5 (formerly 2G5)

Size: 30 ul 100 ul


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USD 159.00

In Stock*

Size
    • 30 ul

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Specifications

Product Data
Clone Name OTI2G5
Applications IF, IHC, WB
Recommended Dilution WB 1:500, IHC 1:150, IF: 1:100
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 95.6 kDa
Gene Name PMS1 homolog 2, mismatch repair system component
Background This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]
Synonyms HNPCC4; PMS2CL; PMSL2
Reference Data
Protein Families Druggable Genome
Protein Pathways Mismatch repair

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