MICA Mouse Monoclonal Antibody [Clone ID: OTI2C3]

CAT#: TA813273

MICA mouse monoclonal antibody, clone OTI2C3

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  View other "OTI2C3" antibodies (2)

USD 379.00

In Stock*

Size
    • 100 ul

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Frequently bought together (2)
Transient overexpression lysate of MHC class I polypeptide-related sequence A (MICA)
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Specifications

Product Data
Clone Name OTI2C3
Applications FC, WB
Recommended Dilution WB 1:500-1000, FLOW 1:100
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human MICA (NP_000238) produced in HEK293T cell.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 42.9 kDa
Gene Name MHC class I polypeptide-related sequence A
Background This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Synonyms MIC-A; PERB11.1
Reference Data

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