SAV1 (NM_021818) Human Untagged Clone

CAT#: SC112869

SAV1 (untagged)-Human salvador homolog 1 (Drosophila) (SAV1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SAV1
• Synonyms: SAV; WW45; WWP4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021818 edited
  GAATTCGGCACGAGGGCCGGCGCCCGGCGCGGAGCCCTAGGGAGGCAGTTCAGCGCGGCC
  TCGGGCCTCGTCGAGAAGGATGCTGTCCCGAAAGAAAACCAAAAACGAAGTGTCCAAGCC
  GGCCGAGGTGCAGGGGAAGTACGTGAAGAAGGAGACGTCGCCTCTGCTTCGGAATCTTAT
  GCCTTCATTCATCCGGCATGGTCCAACAATTCCAAGACGAACTGATATCTGTCTTCCAGA
  TTCAAGCCCTAATGCCTTTTCAACTTCTGGAGATGTAGTTTCAAGAAACCAGAGTTTCCT
  TAGAACTCCAATTCAAAGAACACCTCATGAAATAATGAGAAGAGAAAGCAACAGATTATC
  TGCACCTTCTTATCTTGCCAGAAGTCTAGCAGATGTCCCTAGAGAGTATGGTTCTTCTCA
  GTCATTTGTAACGGAAGTTAGTTTTGCTGTTGAAAATGGAGACTCTGGTTCCCGATATTA
  TTATTCAGACAATTTTTTTGATGGTCAGAGAAAGCGGCCACTTGGAGATCGTGCACATGA
  AGACTACAGATATTATGAATACAACCATGATCTCTTCCAAAGAATGCCACAGAATCAGGG
  GAGGCATGCTTCAGGTATTGGGAGAGTTGCTGCTACATCTTTAGGAAATTTGACTAACCA
  TGGTTCTGAAGATTTACCCCTTCCTCCTGGCTGGTCTGTGGACTGGACAATGAGAGGGAG
  AAAATATTATATAGATCATAACACAAATACAACTCACTGGAGCCATCCTCTTGAGCGAGA
  AGGACTTCCTCCTGGATGGGAACGAGTTGAGTCATCCGAATTTGGAACCTATTATGTAGA
  TCACACAAATAAGAAGGCCCAATACAGGCATCCCTGTGCTCCTAGTGTACCTCGGTATGA
  TCAACCACCTCCTGTCACATACCAGCCACAGCAAACTGAAAGAAATCAGTCCCTTCTGGT
  ACCTGCAAATCCATATCATACTGCAGAAATTCCTGACTGGCTTCAGGTTTACGCACGAGC
  CCCTGTGAAATATGACCACATTCTGAAGTGGGAACTCTTCCAGCTGGCTGACCTGGATAC
  ATACCAGGGAATGCTAAAGTTGCTCTTCATGAAAGAATTGGAGCAGATTGTTAAAATGTA
  TGAAGCATACAGACAAGCCCTTCTTACAGAGTTGGAAAACCGAAAGCAGAGACAGCAGTG
  GTATGCCCAACAACATGGAAAAAATTTTTGAGCTGATTTTTTAAAAATTTAAGTTTTGTA
  AGAGCTTTAAAATATTTTCACAGATAAAAAATTGCAAACAAGTACTCTGGTTAATAAATG
  CTGCTTCCTTTGTGGAAATTATAAAATTCTAACTTTACATGTATTTTGTTATTAGAAATT
  TTCTTTTATTGAATGAGAAAAATTAGTCTATCATTTTAAGAGCCAATATGGCAAACACTT
  TCAAATACTGTATATTAGGAAACTGTTTTGGTATTCTTGATGGAAAAAAACGCAGCGGAA
  ATGTCATTATGAACAGATGTTAAATAGGAAATTATTACTTGTTAACTTCTTACAGCAGTA
  GTACCTTCTTTAAAAAAAAAAAAGAATCTGCGGTATTTTTTTAAAAAAAAAGTTTACTGC
  TGTAGTGTGAAATATTGTCTGGAAAGGGATGGTTTAAATATTACCATGATGTAGTTGAAA
  TATAAAATAGGATTTGGAACCTTATTGTGATAAATATTTATATATGATGTATGTTTGTCT
  CCCCTCTCCAAAGTAAGGAACCCAGCTGGGCGTGGTGGCTCACTCCTGTAATCCCAGCAT
  TTTGGGAGGCCGAGGTGGGTGGACCGCTTGAGTCCACGAGTTTAAGACCAGCCTGGGCAA
  CATGGTGAAGCCCCATCTCTACAAAAAATACAAAAAAATTAGCCGGGTATGATGGTGTGT
  GCCTCTAGTCCCAGCTACTTGGGAGGCTGAGGTCAGAGGATGGCTTGAGCCCAAGAGGCA
  GAGGTTGCAGGGTCAAGATCGCACCACTTGCACTGCAGCCTGAGAGAGAGAGAGCCAGAC
  CTTGTCTCAAAAAAATAAAAAATAAAAAAATAAAAACAAAATAAGGAATCCTTTTAAAGC
  ATGTTGAGAAAGTATTTTTTGGTATGAATGGGTGACGGGCCTTTTAATCTTTCAGGAATA
  CATATAAGCAGGAATACTTAGCCTGTATTGGGAAGGTGCGTGAAACTCAAAGTTGCTAAC
  ATCATCTTCCTTATTTTCAGCCAGTGCTGTTACTGCATTTAGCATGGCTCTGACGAGGCA
  GTGGAGAGTTCCTGACAGCATAGCATACTGCCTTCTGACAGACTGGGTTAAGCTACCAAA
  AATGACAACCAGGGATTCAAAAAAAAAATTTTTGGTCATTAAATCGAATGTATATTATTA
  CTTTTTAATTTTCTAAGTATTTATCACAGGACTTTAACACCATATATTTCCCTCCCAGTT
  TTTCTCCCCTTTTGGTTTAATAGTTAAAACATTTTTCATAATTAGTGCTGTACATTTGAT
  TGCAAACAAATTGGTGATACTTCTAAACTATAACTATAAATCTCTAGAATTCTGTGAATT
  TCAACATTATTTGAAGTAGTTCTTCAGTTATATTTACATGTGTTGTAAATATGTAAATAT
  ACTTTTAGCTTAGGAAGTCTTCCAGAATACAAACTACTCCCAGTTAGATATCAGTGAGTT
  TGAATAACTGAAGAAATGTTGACAATGTTAAGTGTTTGATTTTATATAACAAGCTTATTA
  AATATATTTTTGTGGAAACTAAAAAAAAACAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021818 unedited
  ACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCGGCGCCCGGCGCGGAGCCC
  TAGGGAGGCAGTTCAGCGCGGCCTCGGGCCTCGTCGAGAAGGATGCTGTCCCGAAAGAAA
  ACCAAAAACGAAGTGTCCAAGCCGGCCGAGGTGCAGGGGAAGTACGTGAAGAAGGAGACG
  TCGCCTCTGCTTCGGAATCTTATGCCTTCATTCATCCGGCATGGTCCAACAATTCCAAGA
  CGAACTGATCTCTGTCTTCCAGATTCAAGCCCTAATGCCTTTTCAACTTCTGGAGATGTA
  GTTTCAAGAAACCAGAGTTTCCTTAGAACTCCAATTCAAAGAACACCTCATGAAATAATG
  AGAAGAGAAAGCAACAGATTATCTGCACCTTCTTATCTTGCCAGAAGTCTAGCAGATGTC
  CCTAGAGAGTATGGTTCTTCTCAGTCATTTGTAACGGAAGTTAGTTTTGCTGTTGAAAAT
  GGAGACTCTGGTTCCCGATATTATTATTCAGACAATTTTTTTGATGGTCAGAGAAAGCGG
  CCACTTGGAGATCGTGCACATGAAGACTACAGATATTATGAATACAACCATGATCTCTTC
  CAAAGAATGCCACAGAATCAGGGGAGGCATGCTTCAGGTATTGGGAGAGTTGCTGCTACA
  TCTTTAGGAAATTTGACTAACCATGGGTCTGAAGATTTACCCCTTCCTCCTGGCTGGTCT
  GTGGACTGGACATGAGAGGGAGAAATATATATAGATCATACACANATACCACTCACTGGA
  GCCATCCTCTTGAGCGAAANGGACCTTCTNCTGGATGGGAACGAGNTGAGTCATTCGAAT
  TTGGACCTATATTGTAGATCACACAATAAGAGGNCCATACAGGCATCCCTGTGCTCTAGT
  GTACTCGGATGATCACCACCTCTGTACATACCAGCACAGAACTGAAGAAATAGTCCCTTT
  TGTACTGCAATCTATAACTGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021818 unedited
  CCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGTTTTTTTTAGTTTCCA
  CAAAAATATATTTAATAAGCTTGTTATATAAAATCAAACACTTAACATTGTCAACATTTC
  TTCAGTTATTCAAACTCACTGATATCTAACTGGGAGTAGTTTGTATTCTGGAAGACTTCC
  TAAGCTAAAAGTATATTTACATATTTACAACACATGTAAATATAACTGAAGAACTACTTC
  AAATAATGTTGAAATTCACAGAATTCTAGAGATTTATAGTTATAGTTTAGAAGTATCACC
  CATTTTGTTTGGCATCAAATGTTCAGCCCTAATTTTTGAAAAAGGTTTAACCTTTAAACC
  CAAGGGGGGAAAAAAATGGGGGGGGAAAATTTGGGGGGAAAAACCCCGGGAAAAACCTCC
  AAAAAAAAAAAAAGGGTTTTTCCCCCCCCCCGAGAAAAACCCAAAAATTTTTTTTTTAAA
  ACCCCCCGGGGGTTTTTTTGGGGACCCCCACCCCCCCCCAAAGAGAAGGGTTTTTTTGTT
  TGGAAAAACACCCCCTTCCCCAAAAAACCTTTTTTTTTAAACACCCCCCCTTTTTTAAAA
  AAAAAAAAAAANNTTTTTTTTTTTTNCCCCCCCCCCCCCCCCAACAAAAAATAATTTTTT
  TTTTTTTTTTGAAAAAAAAAAAGGGCCCCCCCCCCCCCCCCAAAAAAAAAANNGTGTTTN
  NNGGGAGGGGGGGGGGGGGGNNATTTNTCTTTTTTTTTTTTTTTAAAAAAAAAAAGGGCG
  CCCCCNCCCTTTCCCCCCGGCGGGGGGGGGGGGGGGGGACCCCCCCCCCCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_021818
• ORF Size: 1152 bp
• Insert Size: 2800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021818.2, NP_068590.1
• RefSeq Size: 3031
• RefSeq ORF: 1152
• Locus ID: 60485
• Domains: WW
• Gene Summary: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]