RIP2 (RIPK2) (NM_003821) Human Untagged Clone

CAT#: SC117734

RIPK2 (untagged)-Human receptor-interacting serine-threonine kinase 2 (RIPK2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RIPK2
• Synonyms: CARD3; CARDIAK; CCK; GIG30; RICK; RIP2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003821 edited
  ATGAACGGGGAGGCCATCTGCAGCGCCCTGCCCACCATTCCCTACCACAAACTCGCCGAC
  CTGCGCTACCTGAGCCGCGGCGCCTCTGGCACTGTGTCGTCCGCCCGCCACGCAGACTGG
  CGCGTCCAGGTGGCCGTGAAGCACCTGCACATCCACACTCCGCTGCTCGACAGTGAAAGA
  AAGGATGTCTTAAGAGAAGCTGAAATTTTACACAAAGCTAGATTTAGTTACATTCTTCCA
  ATTTTGGGAATTTGCAATGAGCCTGAATTTTTGGGAATAGTTACTGAATACATGCCAAAT
  GGATCATTAAATGAACTCCTACATAGGAAAACTGAATATCCTGATGTTGCTTGGCCATTG
  AGATTTCGCATCCTGCATGAAATTGCCCTTGGTGTAAATTACCTGCACAATATGACTCCT
  CCTTTACTTCATCATGACTTGAAGACTCAGAATATCTTATTGGACAATGAATTTCATGTT
  AAGATTGCAGATTTTGGTTTATCAAAGTGGCGCATGATGTCCCTCTCACAGTCACGAAGT
  AGCAAATCTGCACCAGAAGGAGGGACAATTATCTATATGCCACCTGAAAACTATGAACCT
  GGACAAAAATCAAGGGCCAGTATCAAGCACGATATATATAGCTATGCAGTTATCACATGG
  GAAGTGTTATCCAGAAAACAGCCTTTTGAAGATGTCACCAATCCTTTGCAGATAATGTAT
  AGTGTGTCACAAGGACATCGACCTGTTATTAATGAAGAAAGTTTGCCATATGATATACCT
  CACCGAGCACGTATGATCTCTCTAATAGAAAGTGGATGGGCACAAAATCCAGATGAAAGA
  CCATCTTTCTTAAAATGTTTAATAGAACTTGAACCAGTTTTGAGAACATTTGAAGAGATA
  ACTTTTCTTGAAGCTGTTATTCAGCTAAAGAAAACAAAGTTACAGAGTGTTTCAAGTGCC
  ATTTACCTATGTGACAAGAAGAAAATGGAATTATCTCTGAACATACCTGTAAATCATGGT
  CCACAAGAGGAATCATGTGGATCCTCTCAGCTCCATGAAAATAGTGGTTCTCCTGAAACT
  TCAAGGTCCCTGCCAGCTCCTCAAGACAATGATTTTTTATCTAGAAAAGCTCAAGACTGT
  TATTTTATGAAGCTGCATCACTGTCCTGGAAATCACAGTTGGGATAGCACCATTTCTGGA
  TCTCAAAGGGCTGCATTCTGTGATCACAAGACCACTCCATGCTCTTCAGCAATAATAAAT
  CCACTCTCAACTGCAGGAAACTCAGAACGTCTGCAGCCTGGTATAGCCCAGCAGTGGATC
  CAGAGCAAAAGGGAAGACATTGTGAACCAAATGACAGAAGCCTGCCTTAACCAGTCGCTA
  GATGCCCTTCTGTCCAGGGACTTGATCATGAAAGAGGACTATGAACTTGTTAGTACCAAG
  CCTACAAGGACCTCAAAAGTCAGACAATTACTAGACACTACTGACATCCAAGGAGAAGAA
  TTTGCCAAAGTTATAGTACAAAAATTGAAAGATAACAAACAAATGGGTCTTCAGCCTTAC
  CCGGAAATACTTGTGGTTTCTAGATCACCATCTTTAAATTTACTTCAAAATAAAAGCATG
  TAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003821 unedited
  NTTGTTCAAATTTTGNTATACGACTCACTATAGGGCGGCCGCGNAATCGGCACGAGGGGC
  CTCGCTCGTGCAGGGGCGTATCTGGGCGCCTGAGCGCGGCGTGGGAGCCTTGGGAGCCGC
  CGCAGCAGGGGGCACACCCGGAACCGGCCTGAGCGCCCGGGACCATGAACGGGGAGGCCA
  TCTGCAGCGCCCTGCCCACCATTCCCTACCACAAACTCGCCGACCTGCGCTACCTGAGCC
  GCGGCGCCTCTGGCACTGTGTCGTCCGCCCGCCACGCAGACTGGCGCGTCCAGGTGGCCG
  TGAAGCACCTGCACATCCACACTCCGCTGCTCGACAGTGAAAGAAAGGATGTCTTAAGAG
  AAGCTGAAATTTTACACAAAGCTAGATTTAGTTACATTCTTCCAATTTTGGGAATTTGCA
  ATGAGCCTGAATTTTTGGGAATAGTTACTGAATACATGCCAAATGGATCATTAAATGAAC
  TCCTACATAGGAAAACTGAATATCCTGATGTTGCTTGGCCATTGAGATTTCGCATCCTGC
  ATGAAATTGCCCTTGGTGTAAATTACCTGCACAATATGACTCCTCCTTTACTTCATCATG
  ACTTGAAGACTCAGAATATCTTATTGGACAATGAATTTCATGTTAAGATTGCAGATTTTG
  GTTTATCAAAGTGGCGCATGATGTCCCTCTCACAGTCACGAAGTAGCANATCTGCACCAG
  AAGGAGGGACCATTATCTATATGCCACCTGAAAACTATGAACCTGGACCAAAATCAAGGG
  CCAGTATCAAGCACGATATATATAGCTATGCAGTTATCACATGGGNAAGTGTTATCCAGA
  AAACAGCCCTTTTGAAGATGTCACCAATCCTTTTGCAGATATGTATAGGGTGTCACAAGG
  ACATCGACCTGGTATAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003821 unedited
  GACCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTGAAAATAAAAATCCTTTTATGAAACACATTTTTTTTTGAA
  AAACAAGCACTTACATGCTTTTATTTTGAAAGAAATTTAAAAATGGGGATCTAAAAACCA
  CAAGTTTTTCCGGGTAAGGGTGAAAACCCATTTGGTTGGTATCTTTCAATTTTTGGACTA
  TAACTTTGGCAAAATCTTTTCCTTGGATGGCAAAAAGGGCTAAAAATTGGCTGACTTTTG
  AGGGCCTTGTAGGCTTGGGACTAACAAAGTCATAATCCTCTTTTATGAACAAAGCCCTGG
  ACAAAAAGGCATTTAACGACTGGTTAAAGGAGGCTTCTGGCATTTGGGTCACAAAGGCTT
  CCCTTTTGCTCTGGAACCACTGGTGGGCTATACCAAGCTGGAAACGTTTTGAGTTTCCTG
  CAGTTGAAAGTGGATTTATTATTGCTGAAAAACATGGAGTGGTCTTGTGAACACAAAATG
  CACCCCTTTGAAAACCAAAAAAGGTGCTATCCCAACTGTGATTTCCAAGACAGGGATGCC
  GCTTCATAAAATAACAGGCTTGAGCTTTTCTAGATAAAAAATCAATGTCTTGAGGAACTG
  GCAGGAACCTTTAAAGTTCAAGAAACACCCTATTTTTATGGGACTGAGAGGATCCACATG
  ATTCCTCTTGGGGACCATGATTTCACGGTTGTTCACAGATAATTCCTTTTTTTCTTGGCC
  CCTAGGAAATGGCACTTGAACACTTCTGTAACTTGTTTTTTTTAACCGAAAAACACTTCA
  AGAAAAGTATTTTTCAAAGTTTCCAAACTGGTAAAGTCTATTAAAAATTTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003821
• ORF Size: 1623 bp
• Insert Size: 1880
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_003821.4, NP_003812.1
• RefSeq Size: 2521
• RefSeq ORF: 1623
• Locus ID: 8767
• Domains: pkinase, TyrKc, CARD, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Neurotrophin signaling pathway, NOD-like receptor signaling pathway
• Gene Summary: This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]