SP140 (NM_007237) Human Untagged Clone

CAT#: SC318996

SP140 (untagged)-Human SP140 nuclear body protein (SP140), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SP140
• Synonyms: LYSP100; LYSP100-A; LYSP100-B
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_007237, the custom clone sequence may differ by one or more nucleotides
  ATGGCCCAGCAGGGCCAGCAGGGGCAGATGGCAAGTGGAGACAGCAATCTCAACTTCAGG
  ATGGTCGCAGAGATCCAGAACGTAGAGGGTCAGAACCTGCAGGAGCAGGTTTGCCCTGAG
  CCCATTTTCAGGTTCTTCAGAGAAAACAAGGTGGAGATTGCAAGTGCAATAACAAGGCCA
  TTTCCTTTCCTTATGGGCCTCCGAGACCGCTCCTTCATCTCCGAGCAGATGTATGAACAT
  TTTCAAGAAGCTTTTAGAAACCTGGTCCCAGTGACAAGAGTGATGTATTGTGTACTCAGT
  GAACTGGAGAAGACATTTGGCTGGTCACATCTGGAAGCATTGTTCAGCAGGATTAACCTG
  ATGGCCTATCCTGATTTAAACGAGATTTACAGAAGCTTCCAGAATGTATGCTATGAACAC
  TCACCTCTCCAAATGAATAATGTAAACGATTTAGAAGATAGACCCAGATTACTACCATAT
  GGTAAACAAGAGAACAGCAATGCCTGTCATGAAATGGATGATATAGCAGTGCCTCAGGAA
  GCCTTGAGCTCCTCGCCAAGGTGTGAGCCAGGTTTCTCTTCAGAGTCTTGTGAGCAGTTA
  GCTCTCCCAAAGGCTGGTGGAGGAGATGCTGAAGATGCACCCAGCCTACTACCAGGTGGG
  GGAGTGTCCTGTAAACTTGCTATACAAATAGATGAAGGAGAATCAGAAGAAATGCCCAAG
  TTACTGCCTTATGATACAGAAGTTCTAGAAAGCAACGGGATGATAGATGCGGCAAGGACA
  TACAGCACAGCACCAGGGGAGAAACAGGGAGAGGAGGAAGGCAGGAACAGTCCCAGAAAA
  AGAAACCAAGACAAGGAGAAGTACCAAGAGAGTCCAGAGGGAAGAGACAAAGAGACCTTT
  GATCTAAAAACTCCCCAAGTCACTAATGAAGGAGAACCAGAGAAGGGGCTCTGTCTACTA
  CCAGGTGAAGGAGAAGAGGGCAGTGATGACTGTTCAGAAATGTGTGATGGAGAAGAGCCC
  CAGGAAGCCTCTAGCTCCCTAGCAAGATGTGGGTCAGTTTCTTGTTTCTCTACAGAGACC
  TTTGATCTAAAGACTCCCCAAGTCACTAATGAAGGAGAACCAGAGAAGGAGCTCAGTCTA
  CTACCAGGTGAAGGAGAAGAGGGCAGTGATGACTGTTCGGAAATGTGTGATGGAGAAGAG
  CGCCAGGAAGCCTCTAGCTCCCTAGCAAGACGTGGGTCAGTGTCTAGTGAACTAGAAAAT
  CACCCAATGAATGAAGAAGGAGAATCAGAAGAGCTTGCTTCTAGCCTGCTATATGATAAT
  GTACCAGGAGCGGAGCAATCAGCATATGAAAATGAGAAGTGTTCCTGTGTCATGTGTTTC
  TCAGAAGAGGTGCCAGGAAGCCCAGAAGCAAGGACGGAAAGTGATCAAGCGTGTGGCACA
  ATGGATACTGTGGATATTGCAAACAACTCCACTTTGGGAAAACCCAAGAGGAAAAGAAGA
  AAAAAGAGGGGGCATGGCTGGAGCAGAATGAGAATGAGAAGGCAGAAAAACAGCCAACAA
  AATGATAATAGCAAAGCCGACGGCCAGGTGGTCTCCAGTGAAAAGAAGGCGAACGTGAAT
  CTGAAAGACCTTTCCAAGATTAGGGGGAGAAAGAGAGGCAAACCTGGAACCCGCTTCACT
  CAGAGTGACAGAGCTGCACAGAAAAGAGTCCGATCAAGAGCTTCAAGAAAGCACAAAGAT
  GAAACTGTGGATTTTAAGGCTCCTTTGCTTCCAGTGACCTGTGGTGGGGTGAAGGGAATT
  TTACATAAGAAGAAATTGCAGCAAGGAATCTTGGTGAAGTGTATACAGACTGAGGATGGA
  AAATGGTTCACCCCCACGGAATTTGAAATCAAAGGAGGCCATGCAAGATCAAAGAACTGG
  AGGCTGAGTGTGCGCTGTGGCGGGTGGCCCCTACGATGGCTGATGGAGAATGGATTTCTG
  CCTGATCCTCCAAGAATACGTTACAGGAAAAAAAAGAGAATACTGAAGTCTCAAAACAAT
  AGCTCAGTTGACCCTTGTATGAGAAACCTGGATGAGTGTGAGGTGTGCCGGGACGGAGGG
  GAGCTGTTCTGTTGCGACACTTGTTCAAGAGTCTTCCATGAGGACTGTCACATCCCGCCT
  GTGGAAGCTGAGAGGACCCCGTGGAATTGCATCTTCTGCAGGATGAAGGAGTCTCCGGGA
  AGCCAACAGTGTTGTCAGGAATCTGAGGTCCTGGAGAGGCAGATGTGTCCTGAGGAACAG
  TTGAAATGTGAGTTCCTCCTCTTGAAAGTCTATTGCTGTTCTGAGAGCTCCTTTTTTGCC
  AAGATTCCATACTATTATTATATTAGAGAGGCGTGTCAAGGCCTGAAGGAGCCCATGTGG
  TTGGATAAAATCAAGAAAAGGCTGAATGAGCACGGTTACCCCCAAGTGGAGGGGTTTGTA
  CAAGACATGCGCCTCATCTTCCAGAACCACAGGGCCTCTTACAAGTACAAGGATTTTGGC
  CAAATGGGATTTAGACTGGAGGCTGAGTTTGAGAAGAATTTCAAGGAAGTGTTTGCTATT
  CAGGAAACAAATGGGAACAAT
  
• Restriction Sites: Please inquire
• ACCN: NM_007237
• ORF Size: 2604 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007237.3, NP_009168.3
• RefSeq Size: 3269
• RefSeq ORF: 2604
• Locus ID: 11262
• Domains: SAND, BROMO, PHD, Sp100
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments.