TMEM158 (NM_015444) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC224658L2V

Lenti ORF particles, TMEM158 (mGFP-tagged) - Human transmembrane protein 158 (gene/pseudogene) (TMEM158), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TMEM158
• Synonyms: BBP; p40BBP; RIS1
• Mammalian Cell Selection: None
• Vector: pLenti-C-mGFP
• ACCN: NM_015444
• ORF Size: 900 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC224658).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015444.1, NP_056259.1
• RefSeq Size: 1797 bp
• RefSeq ORF: 903 bp
• Locus ID: 25907
• UniProt ID: Q8WZ71
• Cytogenetics: 3p21.31
• Protein Families: Druggable Genome
• MW: 30.4 kDa
• Gene Summary: Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015]