CCL3 (NM_002983) Human Recombinant Protein
CAT#: TP720049
Recombinant protein of human chemokine (C-C motif) ligand 3 (CCL3)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Ser24-Ala92
|
Tag | Tag Free |
Predicted MW | 7.7 kDa |
Concentration | Resuspend the protein to the desired concentration in proper buffer. |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.4. |
Bioactivity | ED50 is 3-10 ng/mL as determined by the ability of Recombinant CCL3 to chemoattract human CCR5 transfected BaF3 mouse proB cells. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_002974 |
Locus ID | 6348 |
UniProt ID | P10147, A0N0R1 |
Cytogenetics | 17q12 |
Synonyms | G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3 |
Summary | 'This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]' |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418970 | CCL3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 99.00 |
|
LY418970 | Transient overexpression lysate of chemokine (C-C motif) ligand 3 (CCL3) |
USD 325.00 |
|
PH310026 | CCL3 MS Standard C13 and N15-labeled recombinant protein (NP_002974) |
USD 2,055.00 |
|
TP310026 | Recombinant protein of human chemokine (C-C motif) ligand 3 (CCL3) |
USD 823.00 |
|
TP723303 | Purified recombinant protein of Human chemokine (C-C motif) ligand 3 (CCL3). |
USD 240.00 |
|
TP790113 | Purified recombinant protein of Human chemokine (C-C motif) ligand 3 (CCL3), esidues 24-92aa, with N-terminal His tag, secretory expressed in HEK293 cells, 50ug |
USD 719.00 |
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