CXCL5 (NM_002994) Human Recombinant Protein
CAT#: TP723725
Purified recombinant protein of Human chemokine (C-X-C motif) ligand 5 (CXCL5 / ENA-78)
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
Human CXCL5, the region of Ala37-Asn114, from gene Accession# NM_002994.3
|
| Tag | Tag Free |
| Predicted MW | 8.4 kDa |
| Concentration | Protein formulated and vialed at >50 ug/mL in specified buffer |
| Purity | >98%, as determined by Coomassie stained SDS-PAGE. |
| Buffer | 1 x PBS |
| Bioactivity | Bioactivity was measured by its property to chemoattract human neutrophils in a dose dependent manner. |
| Endotoxin | Less than 0.01 ng per µg protein as determined by the LAL method |
| Storage | Store at -80°C. |
| Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Reference Data | |
| RefSeq | NP_002985 |
| Locus ID | 6374 |
| UniProt ID | P42830, Q6I9S7 |
| Cytogenetics | 4q13.3 |
| Refseq Size | 2505 |
| Refseq ORF | 342 |
| Synonyms | ENA-78; SCYB5 |
| Summary | 'This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]' |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
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