ORF Clones Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
KCNJ6 Rapid assessment of G protein signaling of four opioid receptors using a real-time fluorescence-based membrane potential assay Eur J Pharmacol, 2020 Oct ORF Clones RG210938
KCNK10 Inhibition of TREK-2 K(+) channels by PI(4,5)P2: an intrinsic mode of regulation by intracellular ATP via phosphatidylinositol kinase Pflugers Arch., 2016 Jun ORF Clones RC222775
KCNK2 Triple arginine residues in the proximal C-terminus of TREK K+channels are critical for the biphasic regulation by PIP2 Am. J. Physiol., Cell Physiol., 2018 Dec ORF Clones RC214082
KCNK2 Identification of critical amino acids in the proximal C-terminal of TREK-2 K(+) channel for activation by acidic pHi and ATP-dependent inhibition Pflugers Arch., 2017 Oct ORF Clones RC214082
KCNK2 Inhibition of TREK-2 K(+) channels by PI(4,5)P2: an intrinsic mode of regulation by intracellular ATP via phosphatidylinositol kinase Pflugers Arch., 2016 Jun ORF Clones RC214082
KCNK2 TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements PLoS ONE, 2015 May ORF Clones RC210180
KCNK3 A unique lower X-gate in TASK channels traps inhibitors within the vestibule BioRxiv, 2019 Jul ORF Clones RC215155
KCNK3 Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity Cell, 2017 Sep ORF Clones MR224294
KCNK9 Hydroxy-a-sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9 Am. J. Physiol. Gastrointest. Liver Physiol., 2015 Jan ORF Clones RN213524
KCNMA1 Characterization of Membrane Patch-Ion Channel Probes for Scanning Ion Conductance Microscopy Small, 2017 Dec ORF Clones RG215099
Kcnmb1 VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical Neurons. ACS chemical neuroscience, 2021 Jun ORF Clones MG201831
KCNMB4 BK Channel ß4 Subunit Influences Sensitivity and Tolerance to Alcohol by Altering its Response to Kinases J. Biol. Chem., 2014 Sep ORF Clones RG202318
KCNN4 Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo Cell Death & Disease, 2022 Dec ORF Clones RC204457
Kcnn4 IK Ca channels control breast cancer metabolism including AMPK-driven autophagy. Cell death & disease, 2022 Nov ORF Clones MC200643
KCNQ1 Dual Mechanisms of Cardiac Action Potential Prolongation by 4-Oxo-Nonenal Increasing the Risk of Arrhythmia; Late Na + Current Induction and hERG K + Channel Inhibition Antioxidants, 2021 Jul ORF Clones RG219869
Kcnq1 Compound Heterozygous KCNQ1 Mutations Causing Recessive Romano–Ward Syndrome: Functional Characterization by Mutant Co-expression Frontiers in Cardiovascular Medicine, 2021 Feb ORF Clones RN214575
KCNQ1 The I channel response to cAMP is modulated by the KCNE1:KCNQ1 stoichiometry Biophysical Journal, 2018 Sep ORF Clones RC219869
Kcnq1 The I Ks Channel Response to cAMP Is Modulated by the KCNE1:KCNQ1 Stoichiometry Biophysical Journal, 2018 Sep ORF Clones RN214575
KCNQ1 A novel role of the antitumor agent tricyclodecan-9-yl-xanthogenate as an open channel blocker of KCNQ1/KCNE1 Eur. J. Pharmacol., 2018 Feb ORF Clones RG219869
Kcnq1 cAMP-dependent regulation of I Ks single-channel kinetics The Journal of General Physiology, 2017 Aug ORF Clones RN214575
KCNQ1 cAMP-dependent regulation of I Ks single-channel kinetics The Journal of General Physiology, 2017 Jul ORF Clones RC219869
Kcnq1 Screen-based identification and validation of four new ion channels as regulators of renal ciliogenesis Journal of Cell Science, 2016 Jun ORF Clones RN214575
KCNQ1 Regulation of Membrane KCNQ1/KCNE1 Channel Density by Sphingomyelin Synthase 1 Am. J. Physiol., Cell Physiol., 2016 May ORF Clones RG219869
KCNQ1 Potassium Channel KCNJ15 is Required for Histamine Stimulated Gastric Acid Secretion Am. J. Physiol., Cell Physiol., 2015 Jun ORF Clones RC212479
Kcnq1 KCNQ1, KCNE2, and Na + -Coupled Solute Transporters Form Reciprocally Regulating Complexes that Affect Neuronal Excitability Science signaling, 2014 Jun ORF Clones RN214575
Kcnq1 Single-channel basis for the slow activation of the repolarizing cardiac potassium current, I Ks Proceedings of the National Academy of Sciences of the United States of America, 2013 Mar ORF Clones RN214575
Kcnq1 Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of I Ks The Journal of General Physiology, 2010 May ORF Clones RN214575
KCNQ2 Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel The Journal of General Physiology, 2011 Sep ORF Clones RG212932
KCNQ2 Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel J. Gen. Physiol., Aug 2011; 138: 341 - 352., 2011 Aug ORF Clones RC212932
KCNQ3 Human KCNQ5 de novo mutations underlie epilepsy and intellectual disability. Journal of neurophysiology, 2022 Jun ORF Clones RG234832
KCNQ3 Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel The Journal of General Physiology, 2011 Sep ORF Clones RG218739
KCNQ3 Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel J. Gen. Physiol., Aug 2011; 138: 341 - 352., 2011 Aug ORF Clones RC218739
KCNQ4 Rare KCNQ4 variants found in public databases underlie impaired channel activity that may contribute to hearing impairment Exp. Mol. Med., 2019 Aug ORF Clones RC220242
KCNQ4 A recurrent mutation in KCNQ4 in Korean families with nonsyndromic hearing loss and rescue of the channel activity by KCNQ activators Hum. Mutat., 2018 Dec ORF Clones RC220242
KCNQ4 Whole-exome sequencing identifies two novel mutations in KCNQ4 in individuals with nonsyndromic hearing loss Sci Rep, 2018 Nov ORF Clones RC220242
KCNT1 Functional Effects of Epilepsy Associated KCNT1 Mutations Suggest Pathogenesis via Aberrant Inhibitory Neuronal Activity International Journal of Molecular Sciences, 2022 Dec ORF Clones SC311132
KCNT1 VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical Neurons ACS Chem. Neurosci., 2020 Oct ORF Clones RC214820
KCNT1 Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy Neurotherapeutics, 2018 Aug ORF Clones RC214820
KCNT1 Characterization of two De novo Kcnt1 mutations in children with malignant migrating partial seizures in infancy Mol. Cell. Neurosci., 2016 Jan ORF Clones RC214820
KCNT2 De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy Ann. Neurol., 2018 May ORF Clones RG216225
KCTD12 Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling The Journal of Biological Chemistry, 2023 Feb ORF Clones RC204577
Kctd13 Regulation of vascular function: roles for Cullin-3 and RhoBTB1 In Ppar?-mediated blood pressure control Thesis, 2015 May ORF Clones MR204825
KCTD16 Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling The Journal of Biological Chemistry, 2023 Feb ORF Clones RC211283
KCTD17 Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling The Journal of Biological Chemistry, 2023 Feb ORF Clones RC206070
KCTD2 Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling The Journal of Biological Chemistry, 2023 Feb ORF Clones RC218957
KCTD20 Kctd20 promotes the development of non-small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients Mol. Carcinog., 2017 Apr ORF Clones RC221607
KCTD5 Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling The Journal of Biological Chemistry, 2023 Feb ORF Clones RC200180
KCTD8 Multiple potassium channel tetramerization domain (KCTD) family members interact with Gβγ, with effects on cAMP signaling The Journal of Biological Chemistry, 2023 Feb ORF Clones RC223904
KDEL Receptor SERCaMP: A carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis Mol. Biol. Cell July 2014, 2014 Jul ORF Clones RC205880
Kdelr2 IMPAD1 and KDELR2 drive invasion and metastasis by enhancing Golgi-mediated secretion. Oncogene, 2020 Jul ORF Clones MR202320