Posts for 5/2024

ST2: Potential Biomarker For Cardiovascular Disease

May 16, 2024

The ST2 gene (also known as IL1RL1) is a potential biomarker of poor prognosis in cardiovascular diseases. ST2 is present in two important isoforms: Membrane-bound ST2 (ST2L) and soluble ST2 (sST2). ST2L binds with IL33 and has a cardioprotective effect like decreased cardiac damage, prevention of apoptosis, lowered inflammatory effect, hypertrophy, and fibrosis. However, the binding of sST2 to IL33 causes the protective effect to...

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