Adrenomedullin (ADM) Rabbit Polyclonal Antibody

CAT#: TA356995

ADM Antibody - C-terminal region

Product Images

WB Suggested Anti-ADM Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human, Rabbit
  Homology: Human: 100%; Rabbit: 91%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 20kDa
• Gene Name: adrenomedullin
• Database Link:
  NP_001115
  Entrez Gene 133 Human
  UniProt ID P35318
• Background: Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
• Synonyms: adrenomedullin; AM; preproadrenomedullin

Reference Data

• Protein Families: Druggable Genome, Secreted Protein