Caspase 10 (CASP10) Rabbit Polyclonal Antibody

CAT#: TA357504

CASP10 Antibody - c-terminal region

Product Images

Host: Rabbit Target Name: CASP10 Sample Type: HCT15 Whole Cell lysates Antibody Dilution: 1.0ug/mlThere is BioGPS gene expression data showing that CASP10 is expressed in HCT15

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  Host: Rabbit Target Name: CASP10 Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the c-terminal region of Human CASP10
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 57kDa
• Gene Name: caspase 10
• Database Link:
  NP_116759
  Entrez Gene 843 Human
  UniProt ID Q92851-4
• Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer.
• Synonyms: ALPS2; CASP-10; FLICE2; MCH4

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Apoptosis, RIG-I-like receptor signaling pathway