TIMP1 Rabbit Polyclonal Antibody

CAT#: TA357545

TIMP1 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: TIMP1 Sample Type: Fetal Kidney lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TIMP1
• Specificity: Expected reactivity: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
  Homology: Cow: 93%; Dog: 86%; Goat: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 79%; Sheep: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 23kDa
• Gene Name: TIMP metallopeptidase inhibitor 1
• Database Link:
  NP_003245
  Entrez Gene 7076 Human
  UniProt ID Q6FGX5
• Background: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
• Synonyms: CLGI; EPA; EPO; FLJ90373; HCI; TIMP; TIMP-1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein