LOX 1 (OLR1) (NM_001172632) Human Recombinant Protein

CAT#: TP720433

Recombinant protein of human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 2.


  View other "LOX 1" proteins (6)

USD 330.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (1)
Rabbit anti-OLR1 Polyclonal Antibody
    • 100 ul

USD 275.00

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Tag C-His
Predicted MW 25.4 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_001166103
Locus ID 4973
UniProt ID P78380
Cytogenetics 12p13.2
Synonyms CLEC8A; LOX1; LOXIN; SCARE1; SLOX1
Summary This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways PPAR signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.