LIF (NM_002309) Human Recombinant Protein

CAT#: TP723889

Purified recombinant protein of Human leukemia inhibitory factor (cholinergic differentiation factor) (LIF)


  View other "LIF" proteins (7)

USD 200.00

5 Days*

Size
    • 10 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Human LIF, the region of Ser23-Phe202, from gene Accession# NM_002309
Tag Tag Free
Predicted MW 20 kDa
Concentration Protein formulated and vialed at >50 ug/mL in specified buffer
Purity >97%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS, pH7.4
Bioactivity The ED50 is 0.03-0.12 ng/ml, corresponding to a specific activity of 8.3-33.3 x 106 units/mg.
Endotoxin Less than 1.0 EU per µg of protein as determine by the LAL method
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Reference Data
RefSeq NP_002300
Locus ID 3976
UniProt ID P15018
Cytogenetics 22q12.2
Refseq Size 3987
Refseq ORF 606
Synonyms CDF; DIA; HILDA; MLPLI
Summary 'The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]'
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.