LIF (NM_002309) Human Recombinant Protein

CAT#: TP720015

Recombinant protein of human leukemia inhibitory factor (cholinergic differentiation factor) (LIF)


  View other "LIF" proteins (7)

USD 330.00

3 Weeks*

Size
    • 10 ug

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Frequently bought together (1)
Rat Monoclonal LIF Antibody (39N7D10)
    • 100 ug

USD 424.00

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Tag tag free
Predicted MW 19.8 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 0.02% Tween 20, pH 7.4
Bioactivity ED50 is less than 0.01 ng/ml as determined by the M1 cell differentiation assay. Specific Activity of 1.0 x 108 IU/mg.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Reference Data
RefSeq NP_002300
Locus ID 3976
UniProt ID P15018
Cytogenetics 22q12.2
Synonyms CDF; DIA; HILDA; MLPLI
Summary The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Protein Families Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.