Indirect ELISA

View as table Download

Rabbit polyclonal anti Hemokinin 1 (ms, rt); purified rabbit IgG

Applications ELISA
Reactivities Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Arg-Ser-Arg-Thr-Arg-Gln-Phe-Tyr-Gly-Leu-Met-NH2 coupled to carrier protein.

Rabbit polyclonal anti Thymosin b4 (hu, bo, horse, rt); neat antiserum

Applications ELISA
Reactivities Human, Bovine, Horse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe- Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu- Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH coupled to carrier protein.

Rabbit polyclonal anti Octreotide , purified IgG

Applications ELISA
Conjugation Unconjugated
Immunogen Synthetic peptide H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol (disulfide bond) coupled to carrier protein.

Rabbit polyclonal anti Dynorphin A (3-14), neat antiserum

Applications ELISA
Conjugation Unconjugated
Immunogen Synthetic peptide H-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp- OH coupled to carrier protein.

guinea pig polyclonal anti Angiotensin II

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH coupled to carrier protein.

Guinea pig polyclonal anti Endothelin-1 (hu, bo, ca, ms, po, rt)

Applications ELISA
Reactivities Human, Bovine, Dog, Mouse, Porcine, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys- Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH, (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) coupled to carrier protein.

Guinea pig polyclonal anti ACTH (1-39) (human); neat antiserum

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro- Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Val-Ala-Glu-Asn- Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH (Disulfide bond) coupled to carrier protein.

Guinea pig polyclonal anti a-CGRP (human) , neat antiserum

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu- Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val- Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2, (Disulfide bond) coupled to carrier protein.

Guinea pig polyclonal anti VIP (hu, ms, rt); diluted antiserum

Applications ELISA
Reactivities Human, Bovine, Porcine, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg- Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 coupled to a carrier protein.

Guinea pig polyclonal anti VIP (human, mouse, rat), neat antiserum

Applications ELISA
Reactivities Human, Bovine, Porcine, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg- Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 coupled to a carrier protein.

Guinea pig polyclonal anti Dynorphin B; neat antiserum

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val- Thr-OH coupled to carrier protein.

Guinea pig polyclonal anti Dynorphin B; diluted antiserum

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val- Thr-OH coupled to carrier protein.

Guinea pig polyclonal anti Galanin (hu); neat antiserum

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly- Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu- Thr-Ser-OH coupled to carrier protein.

Guinea pig polyclonal anti pTH-Related Protein (1-34) (hu, ms, rt); neat antiserum

Applications ELISA
Reactivities Human, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly- Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala- Glu-Ile-His-Thr-Ala-OH (Disulfide bond) coupled to carrier protein.

Calcitonin gene-related peptide 1 (alpha-CGRP), guinea pig anti canine/mouse/rat, polyclonal.

Applications ELISA
Reactivities Canine, Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu- Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val- Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2, (Disulfide bond) coupled to carrier protein.

Rabbit polyclonal anti Neuropeptide Y (bo, po); neat antiserum

Applications ELISA
Reactivities Bovine, Porcine
Conjugation Unconjugated

Guinea pig polyclonal anti human / mouse /rat Corticotropin-Releasing Factor (CRF)

Applications ELISA
Reactivities Human, Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe- His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln- Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2 coupled to carrier protein.

Guinea pig polyclonal anti PACAP-38 (hu, ms, ov, po, rt); neat antiserum

Applications ELISA
Reactivities Human, Mouse, Porcine, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg- Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys- Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 coupled to carrier protein.

Atrial Natriuretic Factor (1-28) (hu, bo, po); diluted antiserum

Applications ELISA
Reactivities Human, Bovine, Porcine
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile- Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH, (Disulfide bond) coupled to carrier protein.

Angiotensin II; purified rabbit IgG

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH coupled to carrier protein.

Rabbit polyclonal anti Angiotensin II, diluted antiserum

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH coupled to carrier protein.

ACTH (1-39) (ms, rt); purified rabbit IgG

Applications ELISA
Reactivities Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro- Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Val-Ala-Glu-Asn- Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH (Disulfide bond) coupled to carrier protein.

ACTH (1-39) (ms, rt); diluted antiserum

Applications ELISA
Reactivities Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro- Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Val-Ala-Glu-Asn- Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH (Disulfide bond) coupled to carrier protein.

Atrial Natriuretic Factor (1-28) (hu, bo, po); purified rabbit IgG

Applications ELISA
Reactivities Human, Bovine, Porcine
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met- Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond) coupled to carrier protein.

Atrial Natriuretic Factor (1-28) (ms, rb, rt); diluted antiserum

Applications ELISA
Reactivities Mouse, Rabbit, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile- Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH, (Disulfide bond) coupled to carrier protein.

Corticotropin-Releasing Factor (CRF), rabbit anti human/mouse/rat, polyclonal, diluted Antiserum for RIA.

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly- Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu- Arg-Arg-His-OH, (Disulfide bond) coupled to carrier protein.

Bradykinin; purified rabbit IgG

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH coupled to a carrier protein.

Calcitonin (salmon I); diluted antiserum

Applications ELISA
Conjugation Unconjugated
Immunogen Synthetic peptide H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys- Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly- Ser-Gly-Thr-Pro-NH2, (Disulfide bond) coupled to carrier protein.

BNP-32 (hu); purified rabbit IgG

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly- Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu- Arg-Arg-His-OH, (Disulfide bond) coupled to carrier protein.

a-CGRP (ms, rt); diluted antiserum

Applications ELISA
Reactivities Canine, Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu- Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val- Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2, (Disulfide bond) coupled to carrier protein.

Bradykinin; diluted antiserum

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH coupled to a carrier protein.

a-CGRP (ms, rt); purified rabbit IgG

Applications ELISA
Reactivities Canine, Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu- Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val- Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2, (Disulfide bond) coupled to carrier protein.

beta-Endorphin (hu); diluted antiserum

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr- Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys- Gly-Glu-OH coupled to carrier protein.

beta-Endorphin, rabbit anti human, polyclonal.

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr- Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys- Gly-Glu-OH coupled to carrier protein.

CRF (hu, ms, rt); purified rabbit IgG

Applications ELISA
Reactivities Human, Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe- His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln- Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2 coupled to carrier protein.

beta-Endorphin (rt); diluted antiserum

Applications ELISA
Reactivities Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr- Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys- Gly-Glu-OH coupled to carrier protein.

beta-Endorphin (rt); purified rabbit IgG

Applications ELISA
Reactivities Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr- Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys- Gly-Glu-OH coupled to carrier protein.

Gastrin Inhibitory Polypeptide, rabbit anti human/porcine, polyclonal, diluted Antiserum for RIA.

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile- Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln- Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH coupled to carrier protein.

Endothelin-1 (hu, bo, ca, ms, po, rt); diluted antiserum

Applications ELISA
Reactivities Human, Bovine, Dog, Mouse, Porcine, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys- Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) coupled to carrier protein.

GRF (hu); diluted antiserum

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys- Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg- Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 coupled to carrier protein.

GLP-1 (7-36) amide (hu, bo, gp, ms, rt); diluted antiserum

Applications ELISA
Reactivities Human, Bovine, Guinea Pig, Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser- Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly- Arg-NH2 coupled to carrier protein.

GRF (hu); purified rabbit IgG

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys- Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg- Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 coupled to a carrier protein.

(Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH (Leuprolide); diluted antiserum

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt coupled to carrier protein.

Orexin A (hu, bo, ca, ms, ov, po, rt); neat antiserum

Applications ELISA
Reactivities Human, Bovine, Canine, Mouse, Porcine, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide Pyr-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys- Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly- Ile-Leu-Thr-Leu-NH2, (Disulfide bonds between Cys6 and Cys12/Cys7 and Cys14), coupled to carrier protein.

Orexin A (hu, bo, ca, ms, ov, po, rt); purified rabbit IgG

Applications ELISA
Reactivities Human, Bovine, Canine, Mouse, Porcine, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide Pyr-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys- Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly- Ile-Leu-Thr-Leu-NH2, (Disulfide bonds between Cys6 and Cys12/Cys7 and Cys14), coupled to carrier protein.

Orexin A (hu, bo, ca, ms, ov, po, rt); diluted antiserum

Applications ELISA
Reactivities Human, Bovine, Canine, Mouse, Porcine, Rat
Conjugation Unconjugated

GRF (hu); neat antiserum

Applications ELISA
Reactivities Human
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys- Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg- Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 coupled to carrier protein.

(Des-Gly10,D-Trp6,Pro-NHEt9)-LHRH (Deslorelin); neat antiserum

Applications ELISA
Reactivities Human, Mammalian
Conjugation Unconjugated
Immunogen Synthetic peptide Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt coupled to carrier protein.

Neuropeptide Y, rabbit anti human/mouse/rat, polyclonal.

Applications ELISA
Reactivities Human, Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala- Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn- Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2

Neuropeptide Y (NPY), rabbit anti human/mouse/rat, polyclonal.

Applications ELISA
Reactivities Human, Mouse, Rat
Conjugation Unconjugated
Immunogen Synthetic peptide H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala- Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn- Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2 coupled to carrier protein.